藥品新增
<31M144> Metronidazole(Efucon ®) (7.5 mg/gm,15gm).
新藥介紹
<31M144> Metronidazole(Efucon ®) (7.5 mg/gm,15gm).
藥理作用/作用機轉 |
After diffusing into the organism, interacts with DNA to cause a loss of helical DNA structure and strand breakage resulting in inhibition of protein synthesis and cell death in susceptible organisms |
適應症/ 劑量 |
TOPI 【Adult】 ●Rosacea: Apply and rub a thin film BID to entire affected areas after washing. 【Pediatric】Infants ≥6 months, Children, and Adolescents: ●Periorificial dermatitis: Apply thin film QD-BID. 『Renal Impairment: Adult』 No dosage adjustment necessary 『Hepatic Impairment: Adult』 No dosage adjustment necessary |
使用禁忌 |
Hypersensitivity to metronidazole, parabens, or other ingredients of the formulation or other nitroimidazole derivatives |
警告/預防 |
Carcinogenic, cns effects, eye irritation, hepatic impairment, superinfection |
不良反應 |
【1% to 10%】 Topical: Hypertension, headache, erythema, contact dermatitis, burning sensation of skin, exacerbation of acne rosacea, pruritus, skin irritation, stinging of the skin, xeroderma, UTI, local hypersensitivity reaction, influenza, URTI |
懷孕用藥分級(FDA) |
B /可能安全 |
健保規範 |
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其他 |
Peripheral neuropathy has been reported with topical products. |